Fri Aug 08 2025

39 articles - From Friday Aug 01 2025 to Friday Aug 08 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

J Crohns Colitis

ECCO-ESGAR-ESP-IBUS Guideline on Diagnostics and Monitoring of Patients with IBD: Part 2.

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ECCO-ESGAR-ESP-IBUS Guideline on Diagnostics and Monitoring of Patients with Inflammatory Bowel Disease: Part 1.

It provides recommendations on requirements for initial diagnosis, detection of complications, the use of monitoring tools in patients with IBD and diagnostics in specific situations, such as pregnancy, postoperatively and for cancer surveillance. The guideline is a joint project of the European Crohn's and Colitis Organization (ECCO), the European Society of Gastrointestinal and Abdominal Radiology, the European Society of Pathology, and the International Bowel Ultrasonography Group under the leadership of ECCO.

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Meta-analysis

meta-analyses and systematic reviews

Pancreas

A Systematic Review of Pain Assessment Domains in Acute Pancreatitis Randomised Controlled Trials.

The assessment of pain in RCTs relies almost entirely on unidimensional pain assessment tools which do not capture the complexity of the pain experience. There is a need for multidimensional pain assessment tools specific to AP, which would allow better assessment of pain in clinical practice and in future trials.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Adaptive Dietary and exercise strategies for weight loss in Adults with Prediabetes Trial (ADAPT): A Sequential Multiple Assignment Randomized Trial.

The group-based program resulted in clinically significant weight loss that was similar between calorie-restricted HC and RC diets. However, counseling to follow a HC diet reduced fasting glucose compared to RC. Patients with obesity and prediabetes who are unable to achieve early weight loss may require more intensive and costly intervention strategies (i.e., meal provisions, supervised exercise etc.) to improve obesity treatment outcomes. , registry number NCT04745572.

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Associations between cross-sectional and long-term food insecurity with dietary quality among middle-aged and older US adults: A Cohort Study from the Health and Retirement Study.

Among adults aged 50 years or older, food insecurity, especially long-term very low food security, was adversely associated with diet quality, highlighting the need for policies to reduce food insecurity and facilitate healthy eating habits.

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Associations of breastfeeding with maternal and child health outcomes: umbrella review.

Our findings support the benefits of BF for mothers and their offspring, underscoring the importance of promoting BF practices to improve maternal and child health outcomes. Url of registration PROSPERO CRD42023447328.

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Associations of diet composition and quality with continuous glucose monitor-derived glycemic metrics in a community-based cohort.

Our findings demonstrate that carbohydrate intake and quality, in addition to overall diet quality, is associated with dynamic fluctuations in glucose levels. Future prospective analysis should examine whether glycemic variability mediates the association between diet and incident diabetes.

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Associations of prior wasting malnutrition with later indicators of glucose tolerance across four countries in Africa and Asia: the SAMPA cohort study.

Childhood PM is associated with greater adult dysglycaemia, whilst adulthood PM may have heterogeneous outcomes dependent on subsequent presence/absence of weight gain. Clinicians and public health managers should be aware of the long-term risk and intervene to promote some weight gain but prevent excess weight gain in people previously malnourished.

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Dietary patterns and risk of Alzheimer's disease and related dementias across five racial and ethnic groups in the Multiethnic Cohort Study.

Healthy dietary patterns in mid- to late-life and improvement in older age were associated with a reduced risk of ADRD in a diverse population. The racial and ethnic heterogeneity in the relationships observed warrants further study.

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Effects of Mediterranean diet or Mindfulness Based-Stress Reduction during Pregnancy on Maternal Gut and Vaginal Microbiota. A sub-analysis of the IMPACT BCN trial.

Pregnancy lifestyle interventions influence maternal gut microbiota.

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Effects of weekly cholecalciferol supplementation of lactating mothers on vitamin D status, and infant growth and gross motor development: a randomized controlled trial in rural Ethiopia.

Maternal cholecalciferol supplementation during lactation using a weekly dose of 15,000 IU safely improves both maternal and infant vitamin D status. Clinical trial registry number The trial was registered on clinicaltrials.gov as NCT02210884.

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Global, regional, and national burden of high sugar-sweetened beverages consumption, 1990-2021, with projections up to 2050: a systematic analysis for the Global Burden of Disease Study 2021.

SSB consumption has increased since 1990 and is projected to rise further by 2050, contributing substantially to the global NCD burden. These trends underscore the urgent need for targeted public health interventions aimed at reducing SSB consumption worldwide.

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Gut microbial community and host intestinal gene expression with combined fish oil and soluble corn fiber compared with corn oil and maltodextrin: A randomized crossover trial in healthy older individuals.

Thirty-day supplementation of SCF + FO compared with MD + CO showed significant shifts in intestinal cell pathways relevant to colorectal cancer with concomitant differences in gut microbial community structure and butyrate-producing taxa.

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Investigating the impact of body weight changes and blood lipids on the risk for mild cognitive impairment in Parkinson´s disease; a prospective cohort study.

High risk for MCI in patients with PD at the time of diagnosis was associated with low levels of P-TG and an interaction between change in BMI and P-TG before diagnosis, suggesting that nutritional factors have complex influence on cognitive function in the prodromal stage of PD.

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Low-fat and Whole Milk Consumption in relation to Cardiovascular and All-Cause Mortality: A prospective cohort study in three Norwegian counties.

In this cohort with high milk consumption, whole milk was associated with higher CVD and all-cause mortality whereas low-fat milk was not. Low-fat milk may be associated with lower risks compared with whole milk.

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Quantification of personalized glycemic sensitivity to food and its potential for precision nutrition in a series of n-of-1 trials.

Our novel PGS provides a framework for quantity differences in glycemic sensitivity among healthy individuals and facilitates further research on tailored dietary advice that improves glucose homeostasis.

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Sex hormone changes in a 24-month dietary and physical activity randomized intervention trial in postmenopausal females: the DAMA study.

Our results suggest that, in healthy postmenopausal females with high breast density, a heathy diet mainly based on plant food may play a role as modulator of plasma estradiol concentration.

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Wild foods as drivers of blood ergothioneine and selenoneine concentrations among Inuit living in Nunavik: results from the cross-sectional Qanuilirpitaa? 2017 survey.

Although comparative data are limited, blood selenoneine and ergothioneine concentrations among Nunavimmiut appear substantially higher than in other non-Indigenous populations. Access to country food is important to maintain the dietary intake of these bioactive food components that may be beneficial for the health of Nunavimmiut.

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ω-3 and ω-6 fatty acid status within a week of birth in a cross-sectional study of very preterm infants.

Preterm infants whose blood was sampled later after birth have lower DHA and AA status relative to those sampled earlier after birth; samples taken at later timepoints are concurrently higher in the fatty acids of linoleic acid and oleic acid, which are the major compositional components of intravenous lipid emulsions routinely administered to preterm infants. The results support calls to develop intravenous feeds closely matching the fatty acid composition of infant blood at birth. The N3RO Trial is registered at the Australian New Zealand Clinical Trial Registry as ACTRN12612000503820 (

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J Crohns Colitis

Machine learning for predicting crohn's disease from routine blood tests years before diagnosis: results from the epi-IIRN cohort.

We were able to detect changes in routinely collected blood tests long before CD diagnosis and to predict future CD using a machine-learning model, which may be used for developing screening and prediction models for prevention strategies.

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Practical Considerations for the use of IL-23p19 Inhibitors in Inflammatory Bowel Disease: How to Choose Between Them and Why it Matters?

Its use in combination with other advanced therapies in selected patients is being explored to enhance therapeutic efficacy and improve long-term outcomes. Further real-world studies are needed to assess its effectiveness and benefits in complex disease phenotypes, including perianal fistulizing Crohn's disease.

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Liver Transpl

The impact of neurologic exam on acceptance of donation after circulatory death liver allografts.

ROC curves for predicting DWIT by number of positive BSRs had areas under the curve of 0.58 and 0.66 for DWIT >30 and 60 minutes. Therefore, we concluded that documentation of positive BSRs is associated with non-utilization of DCD liver allografts, despite having limited ability to predict donor expiration within the appropriate time frame for a successful DCD donation.

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Vancomycin-resistant enterococcal infections in liver transplant recipients: Clinical impact and therapeutic approaches.

With limited antimicrobial options and data available for guidance, treatment can be challenging. This review discusses the epidemiology of VRE infections in patients with end stage liver disease and after liver transplant as well as therapeutic approaches.

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Pancreas

Chymotrypsin B2 (CTRB2) Deletion Variant Induces Endoplasmic Reticulum Stress but does not Increase Risk for Chronic Pancreatitis.

We replicated the ER-stress causing effect of the CTRB2-del variant and confirmed the lack of association with CP. The observations also revealed that epitope-tagging may alter the cellular effects of the CTRB2-del protein. The lack of association between ER stress and CP risk in carriers of the CTRB2-del variant raises the possibility that ER stress is a marker of digestive enzyme misfolding but does not drive CP onset and/or progression.

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Molecular Characterization of Pancreatic Simple Mucinous Cysts with GNAS Mutation: A Case Report and Literature Review.

This is the first report of pancreatic SMC with co-occurring KRAS and GNAS mutations. SMC should be considered a differential diagnosis of pancreatic cystic lesions. Surgical intervention may be warranted based on findings.

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Prevalence of Fluid Overload in a Cohort of Patients with Acute Pancreatitis: Results from a Retrospective Tertiary Single-center Study.

The extent of fluid resuscitation was found to be strongly associated with the prevalence of clinical and radiological signs of pulmonary fluid overload. Furthermore, moderately severe and severe courses of pancreatitis were more frequently observed in excessively hydrated patients.

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Pancreatology

Genome-wide association study identifies FUT2 rs601338 polymorphism linking intra-pancreatic fat deposition to chronic pancreatitis.

This study identified novel genetic variants for pancreatic PDFF and confirmed related genes functions in the pancreas. These findings emphasize the need for regular surveillance of pancreatic fat deposition in the population with a high genetic risk based on FUT2 polymorphism, which could facilitate risk stratification and tailored therapeutic approaches for the primary prevention of CP.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Definitions matter in body composition science.

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Factors influencing uptake and blood levels of ergothioneine and selenoneine.

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High-dose soluble corn fiber and omega-3 fatty acids impact the gut microbiome and the host exfoliome, but are the omega-3s necessary?

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Methodological standards for body composition-an expert-endorsed guide for research and clinical applications: levels, models, and terminology.

Models are also specific to each level. It is crucial for researchers and clinicians to have a clear understanding of what each body component entails and to use accurate terminology to ensure precise assessment, reporting, and interpretation of body composition data.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Liver Transpl

Impact of changing liver transplant exception policies to address blood type disparities in access to transplantation.

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Letter to the editor: Chronic rejection in black pediatric transplant recipients- A call for medical social work integration.

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Reply: Chronic rejection in black pediatric transplant recipients- A call for medical social work integration.

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Retraction: Letter to the Editor: Discrimination in liver transplantation.

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Pancreatology

Non-operative observational strategy for small non-functioning pancreatic neuroendocrine neoplasms: A feasible option?

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Progression of Intraductal Papillary Mucinous Neoplasms (IPMN) is possible after 5 years of follow-up.

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Should gastrointestinal bleeding and impaired mental status be considered organ failure in patients with acute pancreatitis?

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Letters&Replies

Letters to the editors and authors’ replies

Pancreatology

Letter to the Editor: Addressing methodological concerns in the study of viral infections and acute pancreatitis.

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